Recent studies suggest that moderate AS is not a benign condition and is associated with increased mortality and morbidity especially when LV function is already reduced.
The PROGRESS trial
For health care professionals
Important safety information
CAUTION: INVESTIGATIONAL DEVICES. The Edwards SAPIEN 3 and Edwards SAPIEN 3 Ultra transcatheter heart valves are investigational devices when used in patients with moderate aortic stenosis. Limited by Federal (USA) law to investigational use only. These devices are not available for marketing or commercial sale in the United States for patients with moderate aortic stenosis.