O software Acumen Hypotension Prediction Index (HPI) é uma
tecnologia inédita que detecta a probabilidade de um paciente evoluir para um evento hipotensor* antes que ele ocorra.
Vários estudos demonstraram que o software Acumen HPI1-4:
- Consegue redução estatisticamente significativa da hipotensão em cirurgia não-cardíaca quando combinado a um protocolo de tratamento em comparação com o tratamento padrão1,2
- Demonstra habilidades preditivas superiores a outros parâmetros hemodinâmicos, como débito cardíaco (DC), volume sistólico (VS) e alterações na pressão arterial média (PAM)3
- Possui precisão comprovada e confiável4
Veja os resultados desses estudos clínicos.
*Um evento hipotensor é definido como PAM <65 mmhg pelo período mínimo de um minuto.
Referências:
- Hatib, F, Jian Z, Buddi S, et al. Machine-learning algorithm to predict hypotension based on high-fidelity arterial pressure waveform analysis. Anesthesiology 2018; 129(4):663-74.
- Davies SJ, Vistisen ST, Jian Z, et al. Ability of an arterial waveform analysis-derived hypotension prediction index to predict future hypotensive events in surgical patients. Anesth Analg 2019;doi: 10.1213/ANE.0000000000004121.
- Wijnberge M, Geerts BF, Hol L, et al. Effect of a Machine Learning–Derived Early Warning System for Intraoperative Hypotension vs Standard Care on Depth and Duration of Intraoperative Hypotension During Elective Noncardiac Surgery: The HYPE Randomized Clinical Trial. JAMA. Published online February 17, 2020. doi:10.1001/jama.2020.0592
- Schneck, E., Schulte, D., Habig, L., Ruhrmann, S., Edinger, F., Markmann M., Habicher, M., Rickert, M., Koch, C., Sander, M. (2019) Hypotension Prediction Index based protocolized haemodynamic management reduces the incidence and duration of intraoperative hypotension in primary total hip arthroplasty: a single centre feasibility randomised blinded prospective interventional trial. Journal of Clinical Monitoring and Computing
- Salmasi, V., Maheshwari, K., Yang, G., Mascha, E.J., Singh, A., Sessler, D.I., & Kurz, A. (2017). Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney injury and myocardial injury. Anesthesiology, 126(1), 47-65.
- Sun, L.Y., Wijeysundera, D.N., Tait, G.A., & Beattie, W.S. (2015). Association of Intraoperative Hypotension with Acute Kidney Injury after Elective non-cardiac Surgery. Anesthesiology, 123(3), 515-523.
- Walsh, M., Devereaux, P.J., Garg, A.X., Kurz, A., Turan, A., Rodseth, R.N., Cywinski, J., Thabane, L., & Sessler, D.I. (2013). Relationship between Intraoperative Mean Arterial Pressure and Clinical Outcomes after non-cardiac Surgery. Anesthesiology, 119(3), 507-515.
- Kahn, Alonso-Coello and Devereaux, Myocardial injury after non-cardiac surgery, Curr Opin Cardiol, 2014, 29:307-311
- Devereaux and Sessler, Cardiac complications in patients undergoing major non-cardiac surgery, N Engl J Med, 2015, 373(23):2258-2269.
- Sellers, D., Srinivas, C., Djaiani, G. (2018). Cardiovascular complications after non-cardiac surgery. Anaesthesia, 73 (Suppl. 1), 34 - 42.
- van Waes, J., Nathoe, H., Graaff, J., Kemperman, H., de Borst, G., Peelen, L., van Klei, W. (2013). Myocardial Injury After Noncardiac Surgery and its Association With Short-Term Mortality. Circulation, 127, 2264 - 2271.
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