Software Acumen Hypotension Prediction Index
El software Acumen Hypotension Prediction Index (HPI) es la primera tecnología de este tipo que le brinda información sobre la probabilidad de que un paciente tenga tendencia hacia un evento hipotensivo.*
Según varios estudios, el software Acumen HPI tiene las siguientes características:
- Logra una reducción estadísticamente significativa de la hipotensión cuando se combina con un protocolo de tratamiento en cirugía no cardiaca frente al tratamiento de referencia.1,2
- Demuestra una capacidad de predicción de la hipotensión superior a la de los parámetros hemodinámicos frecuentes, como el gasto cardiaco (GC), volumen sistólico (VS) y cambios en la presión arterial media (PAM).3
- Tiene precisión comprobada y fiable.4
Consulte los descubrimientos en estos estudios clínicos.
*Un evento hipotensivo se define como PAM < 65 mmHg por una duración de al menos un minuto.
Referencias:
- Wijnberge, M., Geerts, B., Hol, L., Lemmers, N., Mulder, M., Berge, P., Schenk, J., Terwindt, L., Hollman, M., Vlaar, A., Veelo, D. (2020) Effect of a Machine Learning-Derived Early Warning System for Intraoperative Hypotension vs Standard Care on Depth and Duration of Intraoperative Hypotension During Elective Noncardiac Surgery: The HYPE Randomized Clinical Trial. JAMA Online, February 17, 2020. doi:10.1001/jama.2020.0592 https://jamanetwork.com/journals/jama/article-abstract/2761469
- Schneck, E., Schulte, D., Habig, L., Ruhrmann, S., Edinger, F., Markmann, M., Habicher, M., Rickert, M., Koch, C., Sander, M. (2019) Hypotension Prediction Index based protocolized haemodynamic management reduces the incidence and duration of intraoperative hypotension in primary total hip arthroplasty: a single centre feasibility randomized blinded prospective interventional trial. Journal of Clinical Monitoring and Computing online, November 29, 2019. https://link.springer.com/article/10.1007/s10877-019-00433-6
- Davies SJ, Vistisen ST, Jian Z, et al. Ability of an arterial waveform analysis-derived hypotension prediction index to predict future hypotensive events in surgical patients. Anesth Analg 2020;doi: 10.1213/ANE.0000000000004121. https://journals.lww.com/anesthesia-analgesia/Citation/2020/02000/Ability-of-an-Arterial-Waveform-Analysis-Derived.16.aspx
- Hatib, F., Zhongping, J., Buddi, S., Lee, C., Settels, J., Sibert, K., Rinehart, J., Cannesson, M. (2018). Machine-learning Algorithm to Predict Hypotension Based on High-fidelity Arterial Pressure Waveform Analysis. Anesthesiology 129, 663-74. https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2685008
- Salmasi, V., Maheshwari, K., Yang, G., Mascha, E.J., Singh, A., Sessler, D.I., & Kurz, A. (2017). Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney injury and myocardial injury. Anesthesiology, 126(1), 47-65.
- Sun, L.Y., Wijeysundera, D.N., Tait, G.A., & Beattie, W.S. (2015). Association of Intraoperative Hypotension with Acute Kidney Injury after Elective non-cardiac Surgery. Anesthesiology, 123(3), 515-523.
- Walsh, M., Devereaux, P.J., Garg, A.X., Kurz, A., Turan, A., Rodseth, R.N., Cywinski, J., Thabane, L., & Sessler, D.I. (2013). Relationship between Intraoperative Mean Arterial Pressure and Clinical Outcomes after non-cardiac Surgery. Anesthesiology, 119(3), 507-515.
- Kahn, Alonso-Coello and Devereaux, Myocardial injury after non-cardiac surgery, Curr Opin Cardiol, 2014, 29:307-311
- Devereaux and Sessler, Cardiac complications in patients undergoing major non-cardiac surgery, N Engl J Med, 2015, 373(23):2258-2269.
- Sellers, D., Srinivas, C., Djaiani, G. (2018). Cardiovascular complications after non-cardiac surgery. Anaesthesia, 73 (Suppl. 1), 34 - 42.
- van Waes, J., Nathoe, H., Graaff, J., Kemperman, H., de Borst, G., Peelen, L., van Klei, W. (2013). Myocardial Injury After Noncardiac Surgery and its Association With Short-Term Mortality. Circulation, 127, 2264 - 2271.
- Wijnberge et al. HYPE Protocol supplement: Intraoperative implementation of the hypotension probability indicator (HPI) algorithm – A pilot randomized controlled clinical trial, Supplemental to Effect of a machine learning-derived early warning system for intraoperative hypotension vs standard care on depth and duration of intraoperative hypotension during elective noncardiac surgery: The HYPE Randomized Clinical Trial. JAMA 2020.16 Appendix I.
- Vining, David & Gladish, Gregory. (1992). Receiver operating characteristic curves: a basic understanding. Radiographics : a review publication of the Radiological Society of North America, Inc. 12. 1147-54. 10.1148/radiographics.12.6.1439017.
- Huang, Jin, and C.X. Ling. (2005) Using AUC and Accuracy in Evaluating Learning Algorithms. IEEE Transactions on Knowledge and Data Engineering, vol. 17, no. 3, 2005, pp. 299–310., doi:10.1109/tkde.2005.50.
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