

HARPOON Beating Heart Mitral Valve Repair System
In the treatment of severe degenerative mitral regurgitation, the challenges are known, the future is clear.
We are focused on redefining the surgical experience for patients and surgeons, turning procedural challenges into new opportunities for better outcomes.
Introducing reproducible, beating-heart, off-pump surgical mitral repair
A new procedure designed to improve outcomes in degenerative mitral regurgitation (DMR) repair.
Outcomes
HARPOON system case video
HARPOON system case video
Welcome to the future of surgical mitral valve repair
Elegant simplicity in the least-invasive surgical procedure

Performed off pump on a beating heart—no cardiopulmonary bypass required, significantly reducing patient impact

Based on familiar surgical principles—enables multiple chords to be deployed in mitral valve repair

Options preserved—preserves the ability to perform future mitral valve repair
Reliable reproducibility with real-time confirmation of results

Guided by echocardiography—enables real-time chordal adjustment and confirmation of results
Simplified delivery. Surgical flexibility. Standardised experience.
Small-footprint ePTFE chords with proprietary self-forming knots are easily deployed and securely anchored using the preloaded HARPOON delivery system.
Dedicated hemostatic introducer
Minimises blood loss.
Low-profile (9 Fr) delivery system
Minimises apical incision size.
Proprietary, self-forming double-helix ePTFE knot
Preserves the option for future mitral valve repair
Least-invasive surgical procedure for mitral repair
Facilitates excellent safety and rapid patient recovery.

No cardiopulmonary bypass or sternotomy required; <5cm left thoracotomy incision.
Ability to perform procedure through a non-rib-spreading technique in a 1- to 2-hour time frame, enabling faster return to normal activity.
For reliable repair, seeing is achieving
Know before you close
Collaborative echo guidance allows real-time chordal adjustment on the beating heart, ensuring optimal leaflet coaptation and reduction of MR.
Place
- Accurate placement of knot anchors
- Placement of multiple chords
Adjust
- Titration of chordal length and tensioning
Confirm
- Confirmation of results prior to closing
Learn more about the HARPOON system
The HARPOON System product brochure
The HARPOON System product presentation
Video library
HARPOON system procedure animation
HARPOON system case video
HARPOON system procedure animation
HARPOON system case video
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For professional use
For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).
Edwards devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93/42/EEC bear the CE marking of conformity.
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