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Edwards Lifesciences invites you to the 2026 ANZ THV Training Events

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Introducing SAPIEN 3 Ultra RESILIA

Building on the benefits of the SAPIEN 3 platform

SAPIEN 3 Ultra valve, powered by RESILIA tissue

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*No clinical data are available that evaluate the long-term impact of RESILIA tissue in patients.
*RESILIA tissue tested against tissue from commercially available bovine pericardial valves from Edwards Lifesciences in a juvenile sheep model. Flameng, et al. J Thorac Cardiovasc Surg. 2015;149:340-345.
† RESILIA tissue tested against tissue from commercially available bovine pericardial from Edwards Lifesciences in a juvenile sheep model. Flameng, et al. J Thorac Cardiovasc Surg.

RESILIA tissue reduced calcification when compared to traditional surgical valve tissue treatments1

resilia-tissue-comparison

RESILIA tissue showed significant improvement in calcium-blocking properties

calcium-blocking properties chart

*RESILIA tissue tested against tissue from commercially available bovine pericardial valves from Edwards Lifesciences in a juvenile sheep model. Flameng, et al. J Thorac Cardiovasc Surg. 2015;149:340-345.
*Control valve (6900P) not available for commercial supply in Australia / and or New Zealand


References

  1. Flameng W, et al. A randomized assessment of an advanced tissue preservation technology in the juvenile sheep model. J Thorac Cardiovasc Surg. 2015;149:340 -5.
  2. Mack MJ, Leon MB, Thourani VH, et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med. 2019;380:1695-1705. doi:10.1056/NEJMoa1814052.
  3. Nazif TM, Cahill TJ, Daniels D, et al. Real-world experience with the SAPIEN 3 ultra transcatheter heart valve: a propensity-matched analysis from the United States. Circ Cardiovasc Interv. 2021;14:e010543.
  4. Tarantini G, Nai Fovino L, Le Prince P, et al. Coronary access and percutaneous coronary intervention up to 3 years after transcatheter aortic valve implantation with a balloon-expandable valve. Circ Cardiovasc Interv. 2020;13:e008972.
  5. Mack MJ, Leon MB, Thourani VH, et al. Transcatheter aortic valve replacement in low-risk patients at five years. N Engl J Med. 2023;10.1056/NEJMoa2307447