Products / Heart Valve Repair / Carpentier-Edwards Physio II
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Carpentier-Edwards Physio II Annuloplasty Ring
Invented by Alain F. Carpentier, MD, PhD and David H. Adams, MD

This ring offers the security of a proven design based on forty years of experience in mitral valve reconstruction.1 Integrating fifteen years of new learning about mitral valve anatomy and physiology, the next generation Carpentier-Edwards Physio II ring helps surgeons repair without limits.2

Any annulus, any patient
  • Global shape optimization: evolves from the native D-shape to a more circular shape to accommodate the pathological changes in mitral annular dimensions.
  • Double saddle configuration: maximizes the distribution of stress across the reconstructed mitral valve.3
Ease for every implant
  • Designed by surgeons to improve the implant experience.
  • True sewing cuff design offers a 40% improvement in sewing margin.4
  • An easy-to-access, single-cut removal offers quick ring detachment from the holder.
  • Angled holder improves visualization and line-of-sight to the mitral valve.
  • Windows on the holder permit direct visualization of the repaired coaptation line.
Reproducible confidence
  • Proven design offers remodeling with flexibility.
  • Based on over 100,000 implants of the Carpentier-Edwards Physio ring.5
  • Clinical efficacy demonstrated by 7,000 published patient-years.6-16
Ease of use sizers
  • Single-piece sizer designed to optimize ease of use
  • Extended length handle provides optimal access in MIS or traditional procedures
  • Ergonomic grip enhances sizer handling


Indicated for use in patients with mitral valve insufficiency


Any quotes used in this material are taken from independent third-party publications and are not intended to imply that such third party reviewed or endorsed any of the products of Edwards Lifesciences.

References:
1. Based on the first remodeling ring annuloplasty performed by Prof. Carpentier in 1968. See Carpentier A. La valvuloplastie reconstitutive. Une nouvelle technique de valvuloplastie mitrale. Presse Med. 1969 ; 77 :251-3.
2. Filsoufi F and Carpentier AC. Principles of reconstructive surgery in degenerative mitral valve repair. Semin Thorac Cardiovasc Surg. 2007;19:103-110.
3. Jensen M et al. Saddle-shaped mitral valve annuloplasty rings experience lower forces compared with flat rings. Circulation. 2008;118[suppl 1]:S250-S255.
4. Based on comparison with Carpentier-Edwards Physio ring.
5. Based on the implant patient registry maintained by Edwards Lifesciences.
6. Carpentier AF et al. The Physio Ring: an advanced concept. Ann Thorac Surg. 1995; 60(5):1177-85.
7. Sousa Uva M et al. Initial results of mitral valvuloplasty using the Physio ring. Arch Mal Coeur Vaiss. 1997; 90(6):789-95.
9. Raffoul R et al. Clinical evaluation of the Physio ring. Chest. 1998; 113(5):1296-1301.
9. Casselman FP et al. Mitral valve surgery can now routinely be performed endoscopically. Circulation. 2003; 108[suppl II]:48-54.
10. Bax JJ et al. Restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation results in reverse left ventricular remodeling. Circulation. 2004:110(suppl II)103-8.
11. Accola KD et al. Midterm outcomes using the Physio ring in mitral valve reconstruction: experience in 492 patients. Ann Thorac Surg. 2005; 79(4):1276-83.
12. Chan DT et al. Mitral valve annuloplasty with Carpentier-Edwards Physio ring: Mid-term results. Asian Cardiovasc Thorac Ann. 2006; 14:382-6.
13. Seeburger J et al. Minimal invasive mitral valve repair for mitral regurgitation: results of 1339 consecutive patients. Eur J Cardiothorac Surg. 2008; 34(4):760-5.
14. Braun J et al. Restrictive mitral annuloplasty cures ischemic mitral regurgitation and heart failure. Ann Thorac Surg. 2008; 85:430-7.
15. Perier P et al. Toward a new paradigm for the reconstruction of posterior leaflet prolapse: midterm results of the “respect rather than resect” approach. Ann Thorac Surg. 2008; 86:718-25.
16. Geidel S et al. Restrictive mitral valve annuloplasty for chronic ischemic mitral regurgitation: a 5-year clinical experience with the Physio ring. Heart Surg Forum. 2008; 11(4):E225-30.
Models
Interactive 3-D Model

Implantation Videos
David H Adams MD
CAUTION: Federal (United States) law restricts this device to sale by or on the order of a physician. See instructions for use for full prescribing information, including indications, contraindications, warnings, precautions and adverse events.