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The Mitral Valve

Implanted Magna mitral valve
Mitral Physiology PERIMOUNT Magna Mitral Advantage
In the mitral annulus, the fibrous anterior aspect is anatomically distinct from the muscular posterior aspect giving the annulus an overall saddle-shaped geometry.1,2 The asymmetric valve design optimizes annular conformity while reference markers delineate the outflow tract for optimal hemodynamic positioning in the mitral annulus.
Mitral annular degenerative changes, such as calcification and scar tissue, can result in coaptive challenges between the sewing cuff and annular tissue.5 The valve has a wide, expansive sewing cuff with variable compliance that enhances the coaptive interface between cuff and mitral annular tissue while accommodating variability in suture technique.
Left ventricular wall injury and outflow tract obstruction have been known to result from projection of the stent into the left ventricle.5 The PERIMOUNT Magna mitral valve has the lowest effective profile of any mitral tissue valve, giving it the lowest ventricular projection for any stented mitral valve in the industry.3,4


References
1. Arounlangsy P, et al. Histopathogenesis of early-stage mitral annular calcification. J Med Dent Sci 2004 Mar;51(1):35-44.
2. Jimenez JH, et al. Effects of a saddle shaped annulus on mitral valve function and chordal force distribution: an in vitro study. Ann Biomed Eng 2003 Nov;31(10):1171-81.
3. “Ventricular protrusion” Mosaic bioprostheses brochure UC200103933 EN, Medtronic, Inc. 2001.
4. “Ventricular protrusion” SJM Biocor Valve brochure. ITEM1809/0705/7.5M/EN/YC. St. Jude Medical, Inc. 2005.
5. Gudbjartsson T, Aranki S, Cohn LH. Mechanical/bioprosthetic mitral valve replacement. In: Cohn LH, Edmunds LH Jr., eds. Cardiac Surgery in the Adult. New York; McGraw-Hill 2003:951986.
CAUTION: Federal (United States) law restricts this device to sale by or on the order of a physician. See instructions for use for full prescribing information, including indications, contraindications, warnings, precautions and adverse events.
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